Amtrak services Tech Valley with 15 rail stations in nine counties.
Travel times to the Albany-Rensselaer rail station from:
| New York City |
2 hr 25 min |
| Rutland, VT |
2 hr 45 min |
| Syracuse, NY |
3 hr |
| Newark, NJ |
3 hr 18 min |
| Philadelphia, PA |
4 hr 16 min |
| Rochester, NY |
4 hr 18 min |
| Wilmington, DE |
4 hr 39 min |
| Boston, MA |
5 hr |
| Buffalo, NY |
5 hr 15 min |
| Baltimore, MD |
5 hr 24 min |
| Washington, DC |
6 hr 5 min |
| Montreal, QC |
7 hr 15 min |
| Cleveland, OH |
8 hr 20 min |
| Toronto, ON |
10 hr 15 min |
| Chicago, IL |
16 hr 35 mi |